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The incident took place in the Fatehganj Paschim area when the driver of the ambulance lost control of the vehicle, which rammed a divider and came onto the other side of the road before hitting the truck, Bareilly Police said on Twitter.
Seven people died on the spot.
It is suspected that the ambulance driver may have dozed off which led to the crash.
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Chief Minister Yogi Adityanath has condoled the loss of lives.