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The blast happened at around 4:50 p.m. at the gate of the kindergarten in Fengxian County in east China’s Jiangsu Province when children were leaving the school, officials were quoted as saying by the state-run Xinhua news agency.
Police said they are investigating and have no word yet on injuries or deaths.
Witnesses said there were casualties, but the exact number is unclear, the report said.
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It was not immediately clear what caused the blast, which rocked the kindergarten as parents were picking up children from the school.
Pictures and videos posted online showed at least a dozen people lying outside the gate of the kindergarten, the paper said.
Some victims were seen covered in blood while others appeared to be unconscious and some even with their clothes burned off. Children were seen among the injured.
“About 5 pm, we heard a blast and thought it might have been a gas explosion at a nearby food vendor,” a local shop owner was quoted as saying by online news portal Sohu.
“Many people could be dead,” he said.
In one video clip posted online, a man covered in blood was seen trying to stand up only to collapse again. His clothes appeared to have been burned off.
In a separate video clip, people could be heard shouting: “Blast, blast, dial 110 quickly!”
The gate of the kindergarten appeared to have been horribly bent, with shattered glass littering the scene.
China in the past witnessed knife attacks on kindergarten school children by disgruntled people. An explosion of this magnitude was rare.