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The 14th seeds were trailing 4-6 6-7(4) 1-2 when they conceded their second round match as Bopanna suffered an injury. They had lost at the same stage here last year as well.
The result means that only three Indians are now surviving in the men’s doubles draw. Debutants Vishnu Vardhan and N Sriram Balaji and Divij Sharan with his partner Artem Sitak.
Vardhan and Balaji had ousted top-50 players Wesley Koolhof and Marcus Daniell 7-6(5) 6-4 7-6(4) in their opening round.