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The airline said the 448 passengers, who were returning to Britain after travelling on the MSC Preziosa cruise ship in the Caribbean, and crew were taken to a reception centre near London Gatwick Airport for medical assessment after the plane landed.
It said “a number of customers” had “reported feeling unwell onboard” and that it is conducting a full investigation as to what happened.
A South East Coast Ambulance Service spokesman said it treated about 30 people and that three had been taken to a hospital for further checks.
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The company said there have been no cases of acute stomach ailments on the cruise ship in the last two weeks.