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There were initial reports of 15 people dead.
Firefighters rushed to put out the flames and clear out the patients at the Ibn al-Khatib hospital, which provides care for severe COVID-19 patients in its intensive care unit.
“I don’t know how many victims there are, there are so many burned bodies all over the place,” said Dr Sabah al-Kuzaie, present at the scene.
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Iraqi authorities have not released an official casualty count.
There were at least 120 patients in the hospital at the time of the fire, a doctor at the hospital said.
The fire is believed to have been caused when at least one oxygen cylinder exploded inside the hospital, local media reported.
At least two doctors at the scene confirmed they believed the oxygen cylinder had caused the flame that raged on the second floor of the hospital.
Iraq is in the midst of a severe COVID-19 wave. Daily COVID-19 cases now average above 8,000 cases, the highest since the pandemic broke out in the country last year.
The government is urging the public to get vaccinated, but demand has been low due to widespread mistrust of the health care system and the vaccines in particular.