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Rajat Patidar makes his Test debut with the hosts also bringing in spinner Kuldeep Yadav and pacer Mukesh Kumar for KL Rahul, Ravindra Jadeja and Mohammed Siraj.
England have also handed a maiden Test cap to Shoaib Bashir, who replaces injured Jack Leach while veteran pacer James Anderson comes in place of Mark Wood.
India trail the five-match series 0-1.
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England: Zak Crawley, Ben Duckett, Ollie Pope, Joe Root, Jonny Bairstow, Ben Stokes(c), Ben Foakes(w), Rehan Ahmed, Tom Hartley, Shoaib Bashir, James Anderson.