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The mishap took place on National Highway 75 near the Virupakshi Gate in Mulabagilu Taluk.
The deceased have been identified as a husband and wife duo — Sharif and Mymunnisa –of Vijayawada district of Andhra Pradesh. The health condition of another passenger is said to be critical.
The bus was on its way to Bengaluru from Vijayawada. Passengers alleged rash driving and negligence led to the accident. Soon after the incident, the bus driver and the conductor fled from the spot.
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Mulabagilu Rural police have registered a case and have taken up an investigation.