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Vatican spokesman Matteo Bruni did not respond to a request for comment on the report in the Messaggero newspaper.
Francis canceled a Lent retreat for the first time in his papacy this weekend, after axing all public meetings at the end of last week over the cold.
The new coronavirus has spread from China across much of the world, with Italy among the worst affected with over 2,000 people infected and 52 deaths.
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The Messaggero report did not say when Francis had been tested for the disease.