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The BSE Sensex tumbled 1,264.2 points to 83,002.09 in early trade. The NSE Nifty slumped 345.3 points to 25,451.60.
From the 30 Sensex firms, Tata Motors, Asian Paints, Larsen & Toubro, Axis Bank, Mahindra & Mahindra, Reliance Industries, Maruti, Kotak Mahindra Bank, ICICI Bank and HDFC Bank were the major laggards.
JSW Steel, Tata Steel, Sun Pharma and NTPC were among the gainers.
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The US markets ended marginally higher on Wednesday.
Foreign Institutional Investors (FIIs) offloaded equities worth Rs 5,579.35 crore on Tuesday, according to exchange data.
Global oil benchmark Brent crude climbed 1.15 per cent to USD 74.75 a barrel.
“In Tuesday’s trade, FIIs were net sellers of Rs 5,579 crore, while crude oil prices surged above USD 70 per barrel amid escalating tensions in the Middle East,” said Prashanth Tapse, Senior VP (Research), Mehta Equities Ltd.
Equity markets were closed on Wednesday for Mahatma Gandhi Jayanti.
The BSE benchmark dipped 33.49 points or 0.04 per cent to settle at 84,266.29 on Tuesday. The Nifty ended marginally lower by 13.95 points or 0.05 per cent to 25,796.90.