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The 30-share BSE benchmark tumbled 1,060.64 points or 1.86 per cent to 55,915.35 in late afternoon trade. The NSE Nifty also tanked 317.75 points or 1.86 per cent to 16,751.35.
On Wednesday, the Reserve Bank of India (RBI) increased the benchmark lending rate by 40 basis points to 4.40 per cent in a bid to contain inflation, which has remained stubbornly above the target zone of 6 per cent for the last three months.
The decision follows an unscheduled meeting of the Monetary Policy Committee (MPC), with all six members unanimously voting for a rate hike while maintaining the accommodative stance.
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Meanwhile, international oil benchmark Brent crude jumped 3.63 per cent to USD 108.8 per barrel.
Foreign institutional investors offloaded shares worth Rs 1,853.46 crore on Monday, according to stock exchange data.