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Chidambaram, who was also associated with the nuclear weapons programme, breathed his last at Jaslok Hospital in Mumbai at 3.20 am, the official said.
He was the chairman of the Atomic Energy Commission and Principal Scientific Advisor to the government of India.
Chidambaram was conferred with the Padma Shri and the Padma Vibhushan in 1975 and 1999 respectively.